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Article

Decision-making impairment is related to serotonin transporter promoter polymorphism in a sample of patients with obsessive-compulsive disorder.

Behavioural brain research - 16 Dec 2008

da Rocha Felipe Filardi, Malloy-Diniz Leandro, Lage Naira Vassalo, Romano-Silva Marco Aurélio, de Marco Luiz Armando, Correa Humberto

Abstract excerpt

OBJECTIVE: Decision-making impairment is an important feature of some psychiatric disorders, such as attention-deficit/hyperactivity disorder and substance-use disorders, and is associated with dysfunction of the fronto-subcortical circuit, mainly the orbitofrontal cortex (OFC). Several data reports support significant correlations between decision-making impairment and the serotonin system. Thus, this...

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Identifiers

PMID: 18603313
DOI: 10.1016/j.bbr.2008.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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