Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex differences in compulsive alcohol drinking phenotypes: implications for decision-making and social behavior in a preclinical model.

Psychopharmacology - 1 May 2026

Olmedo-Córdoba Manuela, León José Juan, López-Villegas Álvaro, Martín-González Elena, Moreno-Montoya Margarita

Abstract excerpt

RATIONALE: Compulsivity is increasingly recognized as a transdiagnostic trait that amplifies vulnerability to alcohol use disorders. However, its specific role in shaping social behavior and decision-making remains underexplored. OBJECTIVE: This study aimed to identify a vulnerable phenotype characterized by compulsive alcohol drinking and evaluate its behavioral alterations within the social behavior and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Behavior, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Decision Making

Share to Ethanol

Share to Rats, Wistar

Share to Sex Characteristics

Share to Sex Factors

Share to Social Behavior

Source

Open in PubMed Open full text

Identifiers

PMID: 40956417
DOI: 10.1007/s00213-025-06895-8
PMCID: PMC13242481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex differences in compulsive alcohol drinking phenotypes: implications for decision-making and social behavior in a preclinical model.PMID 40956417Read ↗

Differential Neurobiological Markers in Phenotype-stratified Rats Modeling High or Low Vulnerability to Compulsive Behavior: A Narrative Review.Semantic proximity Read ↗

Chronic Alcohol Consumption Alters Home-Cage Behaviors and Responses to Ethologically Relevant Predator Tasks in MiceSemantic proximity Read ↗

Excessive habit formation in schedule-induced polydipsia: Microstructural analysis of licking among rat strains and involvement of the orbitofrontal cortex.Semantic proximity Read ↗

Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same constructSemantic proximity Read ↗

Sex-associated differences in incentive salience and drinking behavior in a rodent model of alcohol relapseSemantic proximity Read ↗

Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms.Semantic proximity Read ↗

An operant ethanol self-administration paradigm that discriminates between appetitive and consummatory behaviors reveals distinct behavioral phenotypes in commonly used rat strains.Semantic proximity Read ↗

Dopamine-transporter heterozygous rats carrying maternal wild-type allele are more vulnerable to the development of compulsive behavior.Semantic proximity Read ↗

Inter-Individual and Inter-Strain Differences in Cognitive and Social Abilities of Dark Agouti and Wistar Han RatsSemantic proximity Read ↗

Stress vulnerability promotes an alcohol prone phenotype in a preclinical model of sustained depressionSemantic proximity Read ↗

Towards a machine-learning assisted diagnosis of psychiatric disorders and their operationalization in preclinical research: evidence from studies on addiction-like behaviour in individual ratsSemantic proximity Read ↗

Compulsive coping behaviour, developed predominantly by sign-trackers, is exacerbated by chronic atomoxetineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.