Article

RNA Host Response-Based Diagnosis of Tick-Borne Infections using Machine Learning and Generative Artificial Intelligence

2025-09-30

Abstract excerpt

<title>Abstract</title> <p>Accurate diagnosis of tick-borne infections remains challenging due to overlapping clinical presentations and limitations in existing laboratory tests. Here we combined RNA sequencing (RNA-Seq) of 461 whole blood samples with machine learning to identify distinct host gene expression signatures for early Lyme disease (n=79), babesiosis (n=103), and anaplasmosis (n=6), including patients...

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Literature Corpus work: 6ef1022f-381c-57b7-8107-ed0565ead4ee
DOI: 10.21203/rs.3.rs-7643069/v1

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