Article

Strain-specific response to pharmacological cold mimicking in aging mice

2026-01-09

Abstract excerpt

<h4>Background</h4> Aging impairs thermogenic and metabolic flexibility, increasing metabolic disease risk. We examined six aging male mouse strains for responses to chronic topical menthol, a pharmacological cold mimetic. <h4>Material and methods</h4> Male (C57BL/6J, A/J, BALB/c, C3H/hej, DBA/2J, and FVB/NJ) mice were treated with 4g/kg of 10% menthol weight per volume cream once per day or vehicle as control u...

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Literature Corpus work: 6ed8da76-8671-5de8-94ad-c765c86d8d7e
DOI: 10.64898/2026.01.08.698532

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