Article

A translational genomics approach to dissect mechanisms of heart failure and recovery

2016-01-01

Abstract excerpt

Dilated cardiomyopathy (DCM) is a progressive disease of heart muscle leading to end-stage heart failure (HF). In this study I used a novel RNA-Sequencing (RNA-Seq) dataset derived from left ventricle (LV) of a large cohort (n = 126) of patients with this condition. Different bioinformatics approaches were applied to combine data from cases, controls, in vivo and cell-based experimental models of fibrosis, as well...

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Literature Corpus work: 6ebf59fa-7e1d-53ad-96d0-19d2b7c4be94
DOI: 10.25560/65752

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