Article

Distinct Metabolic Signatures Linked to High-Resolution Computed Tomography Radiographic Phenotypes in Stable and Progressive Fibrotic Lung Disease

2025-10-31

Abstract excerpt

<h4>Rationale and Objectives</h4> This study aimed to identify distinct metabolic signatures associated with disease progression by integrating high-resolution computed tomography (HRCT) visual scoring with comprehensive metabolomic profiling. <h4>Materials and Methods</h4> This single-center, cross-sectional study enrolled 60 idiopathic pulmonary fibrosis/interstitial lung disease (IPF/ILD) patients from Decemb...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6e1454d3-7621-55fb-ac0c-68c0d9d2cb62
DOI: 10.1101/2025.10.30.685696

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct Metabolic Signatures Linked to High-Resolution Computed Tomography Radiographic Phenotypes in Stable and Progressive Fibrotic Lung DiseaseDOI 10.1101/2025.10.30.685696Read

Serum profiles of metabolomic and GDF-15 differentiate idiopathic pulmonary fibrosis from other interstital lung diseases: a preliminary studySemantic proximity Read

Histological and genetic features and therapeutic responses of lung cancers explored via the global analysis of their metabolome profile.Semantic proximity Read

Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis – a potential biomarker role for LysoPCSemantic proximity Read

An Aetiological and Observational Cohort study of Interstitial Lung Abnormalities (ILAs) Including Progressive Fibrosing Phenotype Interstitial Lung Diseases in a Large General Medical Check-up Population (Kumamoto ILA study in Japan) (KILA-J)Semantic proximity Read

Elevated serum apolipoprotein B and lipoprotein remodelling distinguish adults with HLH from HLH mimics and controlsSemantic proximity Read

Metabolomic profiling reveals distinct metabolic patterns and a potential circulating biomarker in pre-COPDSemantic proximity Read

From ideal respiratory health to chronic lung disease: indicators of impaired respiratory health.Semantic proximity Read

Lipidomics for diagnosis and prognosis of pulmonary hypertensionSemantic proximity Read

Plasma Lipidomic Signatures Across the Healthy-Pre-COPD-COPD Continuum Identified by Machine Learning.Semantic proximity Read

Novel Lipidomes Profile and Clinical Phenotype Identified in Pneumoconiosis PatientsSemantic proximity Read

Serum metabolites characterize hepatic phenotypes and reveal shared pathways: results from population-based imagingSemantic proximity Read

Metabolic changes of different high-resolution computed tomography phenotypes of COPD after budesonide-formoterol treatment.Semantic proximity Read