Article

Autoantibodies Against Human Renal Glomerular Endothelial Cells in Lupus Nephritis That Induce Endothelial Interferon-Alpha Production

2020-09-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: The pathogenesis of lupus nephritis (LN) remains not fully understood. In this study, we aimed to explore the pathogenic roles of autoantibodies against human renal glomerular endothelial cells (HRGEC) in LN patients.<bold>Methods</bold>: The serum levels of anti-HRGEC antibodies in systemic lupus erythematosus (SLE) patients without LN and LN patients were dete...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6e02cb14-b254-543c-8ae7-2d0704c85954
DOI: 10.21203/rs.3.rs-72269/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Autoantibodies Against Human Renal Glomerular Endothelial Cells in Lupus Nephritis That Induce Endothelial Interferon-Alpha ProductionDOI 10.21203/rs.3.rs-72269/v1Read

Secondary Analysis of Microarray Data Reveals Immune-Related Key Genes and Pathways in Chronic Spontaneous UrticariaSemantic proximity Read

The Risk Factors for Lupus NephritisSemantic proximity Read

Mesangial Cell-Specific Antibodies Are Central to the Pathogenesis of Lupus NephritisSemantic proximity Read

Unraveling the Link between Interferon-α and Systemic Lupus Erythematosus: From the Molecular Mechanisms to Target TherapiesSemantic proximity Read

The dysfunctions of complement factor H in lupus nephritis.Semantic proximity Read

Interrelation of T-cell Cytokines and Autoantibodies in Lupus Nephritis: A Cross-sectional StudySemantic proximity Read

Peripheral CD4CD8 Double Positive T Cells: A Potential Marker to Evaluate Kidney Damage Susceptibility During SLESemantic proximity Read

An Emerging Role for Anti-DNA Antibodies in Systemic Lupus ErythematosusSemantic proximity Read

Scleroderma-specific autoantibodies embedded in immune complexes mediate endothelial damage: an early event in the pathogenesis of systemic sclerosisSemantic proximity Read

Co-Positivity for Anti-dsDNA, -Nucleosome and -Histone Antibodies in Lupus Nephritis Is Indicative of High Serum Levels and Severe NephropathySemantic proximity Read

Glomerular Autoimmune Multicomponents of Human Lupus Nephritis In VivoSemantic proximity Read

Role of anti-DNA antibodies in the pathogenesis of lupus nephritisSemantic proximity Read