Article

Motor and Non-Motor Effects of Acute Mptp in Adult Zebrafish: Insights into Parkinson’s Disease

2025-01-17

Abstract excerpt

Parkinson's disease (PD), the second most common neurodegenerative disorder, involves the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, resulting in motor and non-motor symptoms. The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is widely used to develop chemical models of PD. This study evaluates the effects of acute MPTP exposure (3 x 150 mg/kg bw, intraper...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6e025ad7-5c72-5029-90ca-2dbef62a6a57
DOI: 10.20944/preprints202501.1275.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Motor and Non-Motor Effects of Acute Mptp in Adult Zebrafish: Insights into Parkinson’s DiseaseDOI 10.20944/preprints202501.1275.v1Read

Motor and Non-Motor Effects of Acute MPTP in Adult Zebrafish: Insights into Parkinson’s DiseaseSemantic proximity Read

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Treated Adult Zebrafish as a Model for Parkinson’s DiseaseSemantic proximity Read

Phenotypic Profiling of MPTP-Induced Parkinsonian-like Behavioral Phenotypes in Zebrafish Larvae Based on Behavioral Experiment.Semantic proximity Read

Studying the Pathophysiology of Parkinson’s Disease Using ZebrafishSemantic proximity Read

Modeling Parkinson’s Disease in ZebrafishSemantic proximity Read

1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine induced Parkinson's disease in zebrafishSemantic proximity Read

Characterization of neurobehavioral pattern in a zebrafish 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced model: A 96-hour behavioral studySemantic proximity Read

Parkinsonism Reversal and Dopaminergic Resilience: Lessons from a Rotenone-induced Parkinson’s Disease ModelSemantic proximity Read

A Critical Review of Zebrafish Models of Parkinson’s DiseaseSemantic proximity Read

Identification of antiparkinsonian drugs in the 6-hydroxydopamine zebrafish model.Semantic proximity Read

Rotenone exposure causes features of Parkinson`s disease pathology linked with muscle atrophy in developing zebrafish embryoSemantic proximity Read

Parkinson’s Disease-Induced Zebrafish Models: Focussing on Oxidative Stress Implications and Sleep ProcessesSemantic proximity Read