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Article

Identification of antiparkinsonian drugs in the 6-hydroxydopamine zebrafish model.

Pharmacology, biochemistry, and behavior - 1 Feb 2020

Vaz Rita L, Sousa Sara, Chapela Diana, van der Linde Herma C, Willemsen Rob, Correia Ana D, Outeiro Tiago F, Afonso Nuno D

Abstract excerpt

Parkinson's disease (PD) is known as a movement disorder due to characteristic motor features. Existing therapies for PD are only symptomatic, and their efficacy decreases as disease progresses. Zebrafish, a vertebrate in which parkinsonism has been modelled, offers unique features for the identification of molecules with antiparkinsonian properties. Here, we developed a screening assay for the selection of...

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PMID: 31785245
DOI: 10.1016/j.pbb.2019.172828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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