Article

Pathogen evolution within and between hosts with applications to the pneumococcus and SARS-CoV-2

2020-01-01

Abstract excerpt

The tracking of a pathogen's evolution over different timescales is essential: for the design of vaccines, to control antibiotic resistance, for the surveillance of disease, to identify transmission chains and to understand the mechanisms behind the pathogen’s evolution. Although the first bacterial genome was sequenced in 1995, techniques and costs have only recently enabled the large scale study of the evolution...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6da4d6f2-3dbe-58c3-9b3e-2dd068bcc22c
DOI: 10.17863/cam.70503

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pathogen evolution within and between hosts with applications to the pneumococcus and SARS-CoV-2DOI 10.17863/cam.70503Read

Inference of infectious disease transmission using multiple genomes per hostSemantic proximity Read

Insights from Genomics into Bacterial Pathogen PopulationsSemantic proximity Read

Molecular evolution of biological sequencesSemantic proximity Read

Population Gene Introgression and High Genome Plasticity for the Zoonotic Pathogen Streptococcus agalactiaeSemantic proximity Read

Different evolutionary trends form the twilight zone of the bacterial pan-genomeSemantic proximity Read

Population genetics and evolution of the pan-genome of Streptococcus pneumoniae.Semantic proximity Read

Transcriptome remodeling contributes to epidemic disease caused by the human pathogen <i>Streptococcus pyogenes</i>Semantic proximity Read

A phylogenetic method to perform genome-wide association studies in microbes that accounts for population structure and recombinationSemantic proximity Read

Genome-wide detection of selection and other evolutionary forces.Semantic proximity Read

Analysing pneumococcal invasiveness using Bayesian models of pathogen progression ratesSemantic proximity Read

A natural history of AMR in <i>Klebsiella pneumoniae</i> : Global diversity, predictors, and predictions of evolutionary pathwaysSemantic proximity Read

Rapid evolution bacteria reveal pathogenic mechanisms and clinical riskSemantic proximity Read