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The transcriptional regulator Lrp activates the expression of genes involved in tilivalline enterotoxin biosynthesis in <i>Klebsiella oxytoca</i>

2024-03-03

Abstract excerpt

<h4>ABSTRACT</h4> The toxigenic Klebsiella oxytoca strains secret the tilivalline enterotoxin, which causes antibiotic-associated hemorrhagic colitis. The tilivalline is a non-ribosomal peptide synthesized by enzymes encoded in two divergent operons clustered in a pathogenicity island. The transcriptional regulator Lrp ( l eucine-responsive r egulatory p rotein) controls the expression of several bacterial ge...

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Literature Corpus work
6d6dd3a3-5566-536b-aa02-46c210196946
DOI
10.1101/2024.02.29.582825
Open publication

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