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Article

The Transcriptional Regulator Lrp Contributes to Toxin Expression, Sporulation, and Swimming Motility in Clostridium difficile.

Frontiers in cellular and infection microbiology - 1 Jan 2019

Chen Kuan-Yu, Rathod Jagat, Chiu Yi-Ching, Chen Jenn-Wei, Tsai Pei-Jane, Huang I-Hsiu

Abstract excerpt

Clostridium difficile is a Gram-positive, spore-forming bacterium, and major cause of nosocomial diarrhea. Related studies have identified numerous factors that influence virulence traits such as the production of the two primary toxins, toxin A (TcdA) and toxin B (TcdB), as well as sporulation, motility, and biofilm formation. However, multiple putative transcriptional regulators are reportedly encoded in the...

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Identifiers

PMID: 31681632
DOI: 10.3389/fcimb.2019.00356
PMCID: PMC6811523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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