Discovery of tREP-18, a novel class of <i>t</i> RNA encoded peptide with potent leishmanicidal activity

Abstract excerpt

In the post genomic era, tRNA-derived fragments have emerged as a new class of non-coding gene regulators, those play crucial roles both at the transcriptional and translational levels, in different cellular biogenesis. However, none of the studies has ever asked whether tRNAs can also be translated into peptides with any biological significance. Thus, we present a novel hypothesis which suggested that; design and...

Topics

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• Biochemical and Molecular Research
• Mutation
• Parasites and Host Interactions
• Protein Biosynthesis
• Research on Leishmaniasis Studies
• RNA, Transfer
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

be63e011-52e7-5523-8508-81a928802275

DOI

10.1101/2020.10.04.325217