Article

Whole-exome Sequencing Study of Hypospadias

2022-01-21

Abstract excerpt

<h4>ABSTRACT</h4> While hypospadias is one of the most common male congenital disorders, the missing heritability contributed by rare variants with larger effects is poorly understood. To systematically explore the variant patterns in the developing of hypospadias, we performed whole exome sequencing (WES) in 191 severe hypospadias cohort and three trios. Subsequent RNA sequencing of 12 severe hypospadiac foreskin...

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Literature Corpus work: 6d26e4d7-98d1-53a7-860b-603068c1ce52
DOI: 10.1101/2022.01.19.22269564

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