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Article

Utility of genetic work-up for 46, XY patients with severe hypospadias.

Journal of pediatric urology - 1 Jun 2023

Srivastava Priya, Tenney Jessica, Lodish Maya, Slavotinek Anna, Baskin Laurence

Abstract excerpt

OBJECTIVE: Hypospadias is a common congenital abnormality that has been increasing in prevalence over the last decades. Historically, 46, XY patients with severe hypospadias and descended scrotal testes at birth have frequently lacked a genetic diagnosis. Platforms for molecular genetic testing have become more readily available and can offer an insight into underlying genetic causes of severe hypospadias. The...

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PMID: 36496321
DOI: 10.1016/j.jpurol.2022.11.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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