Article

Modelling haplotypes with respect to reference cohort variation graphs

2017-01-20

Abstract excerpt

Current statistical models of haplotypes are limited to panels of haplotypes whose genetic variation can be represented by arrays of values at linearly ordered bi- or multiallelic loci. These methods cannot model structural variants or variants that nest or overlap. A variation graph is a mathematical structure that can encode arbitrarily complex genetic variation. We present the first haplotype model that operate...

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Literature Corpus work: 6d0d8b44-bdac-5233-a3eb-f0db2eec2cb8
DOI: 10.1101/101659

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