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Article

Modelling haplotypes with respect to reference cohort variation graphs.

Bioinformatics (Oxford, England) - 15 Jul 2017

Rosen Yohei, Eizenga Jordan, Paten Benedict

Abstract excerpt

MOTIVATION: Current statistical models of haplotypes are limited to panels of haplotypes whose genetic variation can be represented by arrays of values at linearly ordered bi- or multiallelic loci. These methods cannot model structural variants or variants that nest or overlap. RESULTS: A variation graph is a mathematical structure that can encode arbitrarily complex genetic variation. We present the first...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28881971
DOI: 10.1093/bioinformatics/btx236
PMCID: PMC5870562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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