Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy

Abstract excerpt

Background: Epilepsy, a common neurological disorder, is characterized by susceptibility to recurrent seizures. Increasing evidence suggests that autophagy plays a crucial role in the initiation and progression of epilepsy. However, the precise mechanisms by which autophagy deficiencies involved in epileptogenesis are still not fully understood. Methods: Two datasets of epilepsy (GSE143272 and GSE256068) were...

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