Article

Altered DNA methylation in ion transport and immune signalling genes is associated with severity in Pancreatic Ductal Adenocarcinoma

2021-06-14

Abstract excerpt

<h4>Background</h4> Pancreatic ductal adenocarcinoma (PDAC) is one of the leading cancers worldwide and has a poor survival, with a relative five-year survival rate of only 8.5%. In this study we investigated epigenetic marksassociated with PDAC severity and prognosis, through studying alterations in DNA methylation patterns. <h4>Methods</h4> DNA methylome for tumor and adjacent normal tissue samples from PDAC p...

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Literature Corpus work: 6cd1de6d-ff69-5a9d-ae53-c7d1a973ed56
DOI: 10.1101/2021.06.14.448193

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