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Leveraging epigenetic alterations in pancreatic ductal adenocarcinoma for clinical applications

23 Jan 2025

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by late detection and poor prognosis. Recent research highlights the pivotal role of epigenetic alterations in driving PDAC development and progression. These changes, in conjunction with genetic mutations, contribute to the intricate molecular landscape of the disease. Specific modifications in DNA methylation, histone marks,...

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PMID: 39863139
DOI: 10.1016/j.semcancer.2025.01.003

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