Article

Refining physico-chemical rules for herbicides using an antimalarial library

2020-10-27

Abstract excerpt

<h4>ABSTRACT</h4> Successful herbicides, like drugs, have physico-chemical properties that usually fall within certain limits. A recent analysis of 334 herbicides showed similar properties to the ‘rule of five’ for human orally-delivered drugs, but herbicides diverged from this for proton donors, partition coefficients and molecular weight. To refine rules for herbicides, we exploited the close evolutionary relat...

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Literature Corpus work: 6cbad2eb-32ac-5345-b028-0a832e91645c
DOI: 10.1101/2020.10.27.356576

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