Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Abstract excerpt

Abstract Identification of novel drug targets is a key component of modern drug discovery. While antimalarial targets are often identified through the mechanism of action studies on phenotypically derived inhibitors, this method tends to be time- and resource-consuming. The discoverable target space is also constrained by existing compound libraries and phenotypic assay conditions. Leveraging recent advances in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hepatitis C virus research
• Share to Malaria Research and Control
• Share to vaccines and immunoinformatics approaches