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Article

Pharmacogenetics of warfarin.

Annual review of medicine - 1 Jan 2010

Kamali Farhad, Wynne Hilary

Abstract excerpt

Warfarin is a drug with a narrow therapeutic index and a wide interindividual variability in dose requirement. Because it is difficult to predict an accurate dose for an individual, patients starting the drug are at risk of thromboembolism or bleeding associated with underdosing or overdosing, respectively. Single nucleotide polymorphisms in the cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKOR)...

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Source

Identifiers

PMID: 19686083
DOI: 10.1146/annurev.med.070808.170037

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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