Article

The Lyme Disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector

2021-09-15

Abstract excerpt

Adiponectin-mediated pathways contribute to mammalian homeostasis; however, little is known about adiponectin and adiponectin receptor signaling in arthropods. In this study, we demonstrate that Ixodes scapularis ticks have an adiponectin receptor-like protein (ISARL) but lack adiponectin – suggesting activation by alternative pathways. ISARL expression is significantly upregulated in the tick gut after Borreli...

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Identifiers and source

Literature Corpus work: 6cad1965-dad9-5187-a189-735ded74623e
DOI: 10.1101/2021.09.13.460039

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