Article

Eph Receptor Tyrosine Kinases Are Functional Entry Receptors for Murine Gammaherpesvirus 68

2025-06-05

Abstract excerpt

Interactions between viral glycoproteins and cellular receptors determine virus tropism and represent promising targets for vaccines. Eph receptor tyrosine kinases are conserved receptors for the human oncogenic gammaherpesviruses, Kaposi sarcoma herpesvirus (KSHV) and Epstein-Barr virus (EBV), and mediate entry into target cells by interaction of the viral gH/gL glycoprotein complex. To evaluate the use of murine...

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Literature Corpus work: 6c83fbf5-51dc-56b3-b2e5-bd764f2261a5
DOI: 10.1101/2025.06.05.657996

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