Article

A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus

2019-08-05

Abstract excerpt

The prototypic henipaviruses (HNV), Hendra (HeV) and Nipah (NiV), are emergent zoonotic pathogens responsible for frequent and fatal outbreaks of severe disease in domestic animals and humans. The HNV attachment glycoprotein (G) is a critical determinant of host-species and cell-type tropism. Utilization of highly conserved B-type ephrin ligands as functional entry receptors engenders HNVs with a broad permissive...

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Literature Corpus work: 701fd13f-5e87-55e8-bfa2-43588dce5a99
DOI: 10.1101/724138

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