Article

Enhancer control of miR-155 expression in Epstein-Barr virus infected B cells

2018-05-01

Abstract excerpt

<h4>ABSTRACT</h4> The oncogenic microRNA-155 (miR-155) is the most frequently upregulated miRNA in Epstein-Barr virus (EBV)-positive B cell malignancies and is upregulated in other non-viral lymphomas. Both the EBV nuclear antigen 2 (EBNA2), and B cell transcription factor, interferon regulatory factor 4 (IRF4) are known to activate transcription of the host cell gene from which miR-155 is processed ( miR-155HG,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6c668988-d67d-5d21-b144-03f5a08a5d48
DOI: 10.1101/311886

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Enhancer control of miR-155 expression in Epstein-Barr virus infected B cellsDOI 10.1101/311886Read

Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B CellsSemantic proximity Read

Epstein-Barr Virus-Induced miR-155 Attenuates NF-κB Signaling and Stabilizes Latent Virus PersistenceSemantic proximity Read

Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathwaySemantic proximity Read

Multiple viral microRNAs regulate interferon release and signaling early during infection with Epstein-Barr virusSemantic proximity Read

EBV-HSA-RegDB: A database of regulatory interactions between Epstein–Barr virus and human miRNAsSemantic proximity Read

A Kaposi's Sarcoma-Associated Herpesvirus-Encoded Ortholog of MicroRNA miR-155 Induces Human Splenic B-Cell Expansion in NOD/LtSz-scid IL2Rγ <sup>null</sup> MiceSemantic proximity Read

Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr VirusSemantic proximity Read

The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cisSemantic proximity Read

RUNXsuper-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growthSemantic proximity Read

Epstein-Barr virus-mediated dysregulation of human microRNA expressionSemantic proximity Read

The Role of microRNA-155 as a Biomarker in Diffuse Large B-Cell LymphomaSemantic proximity Read

Virally Induced Cellular MicroRNA miR-155 Plays a Key Role in B-Cell Immortalization by Epstein-Barr VirusSemantic proximity Read