Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Virally Induced Cellular MicroRNA miR-155 Plays a Key Role in B-Cell Immortalization by Epstein-Barr Virus

16 Sept 2010

Abstract excerpt

Infection of resting primary human B cells by Epstein-Barr virus (EBV) results in their transformation into indefinitely proliferating lymphoblastoid cell lines (LCLs). LCL formation serves as a model for lymphomagenesis, and LCLs are phenotypically similar to EBV-positive diffuse large B-cell lymphomas (DLBCLs), which represent a common AIDS-associated malignancy. B-cell infection by EBV induces the expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20844043
DOI: 10.1128/jvi.01248-10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Virally Induced Cellular MicroRNA miR-155 Plays a Key Role in B-Cell Immortalization by Epstein-Barr VirusPMID 20844043Read ↗

Epstein-Barr Virus-Induced miR-155 Attenuates NF-κB Signaling and Stabilizes Latent Virus PersistenceSemantic proximity Read ↗

Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B CellsSemantic proximity Read ↗

Epstein-Barr virus-mediated dysregulation of human microRNA expressionSemantic proximity Read ↗

The Role of microRNA-155 as a Biomarker in Diffuse Large B-Cell LymphomaSemantic proximity Read ↗

Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathwaySemantic proximity Read ↗

MiR-155/miR-150 network regulates progression through the disease phases of chronic lymphocytic leukemiaSemantic proximity Read ↗

MicroRNAs in lymphoma, from diagnosis to targeted therapySemantic proximity Read ↗

The Epstein-Barr Virus (EBV)-Induced Tumor Suppressor MicroRNA MiR-34a Is Growth Promoting in EBV-Infected B CellsSemantic proximity Read ↗

Epstein-Barr Virus Latent Membrane Protein 1 Regulates Host B Cell MicroRNA-155 and Its Target FOXO3a via PI3K p110α ActivationSemantic proximity Read ↗

Re‐expression of micro<scp>RNA</scp>‐150 induces <scp>EBV</scp>‐positive <scp>B</scp>urkitt lymphoma differentiation by modulating c‐Myb <i>in vitro</i>Semantic proximity Read ↗

A Kaposi's Sarcoma-Associated Herpesvirus-Encoded Ortholog of MicroRNA miR-155 Induces Human Splenic B-Cell Expansion in NOD/LtSz-scid IL2Rγ <sup>null</sup> MiceSemantic proximity Read ↗

MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.