Article

Molnupiravir combined with different repurposed drugs further inhibits SARS-CoV-2 infection in human nasal epithelium <i>in vitro</i>

2022-01-10

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in late 2019, has caused a worldwide pandemic with unprecedented economic and societal impact. Currently, several vaccines are available, and multitudes of antiviral treatments have been proposed and tested. Although many of the vaccines show high clinical efficacy, they are not equally accessible worldwide. Additionally, due to the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6bd16891-0000-5b97-8fe8-2fe5b578edad
DOI: 10.1101/2022.01.10.475377

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Molnupiravir combined with different repurposed drugs further inhibits SARS-CoV-2 infection in human nasal epithelium <i>in vitro</i>DOI 10.1101/2022.01.10.475377Read

Antiviral drug synergy and mutational signatures in different epithelial cell models of RSV and hPIV infectionSemantic proximity Read

Use of Stem Cell-Derived Cardiomyocyte and Nasal Epithelium Models to Establish a Multi-Tissue Model Platform to Validate Repurposed Drugs Against SARS-CoV-2 InfectionSemantic proximity Read

Molnupiravir, an Oral Antiviral Treatment for COVID-19Semantic proximity Read

Identification of Broad Anti-Coronavirus Chemical Agents for Repurposing Against SARS-CoV-2 and Variants of ConcernSemantic proximity Read

Antiviral activity of Molnupiravir precursor NHC against SARS-CoV-2 Variants of Concern (VOCs) and implications for the therapeutic window and resistanceSemantic proximity Read

Drug repurposing platform for deciphering the druggable SARS-CoV-2 interactomeSemantic proximity Read

Repurposing Molnupiravir for COVID-19: The Mechanisms of Antiviral ActivitySemantic proximity Read

Synergistic interactions of repurposed drugs that inhibit Nsp1, a major virulence factor for COVID-19Semantic proximity Read

Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In VitroSemantic proximity Read

Viral polymerase binding and broad-spectrum antiviral activity of molnupiravir against human seasonal coronavirusesSemantic proximity Read

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in miceSemantic proximity Read

Combined Molnupiravir and Nirmatrelvir Treatment Improves the Inhibitory Effect on SARS-CoV-2 in Rhesus MacaquesSemantic proximity Read