Article
Oxidative Stress, Neuroinflammation, and Microvascular Damage in Neurodegenerative Diseases: Mechanistic Insights and Therapeutic Approaches
2025-11-10
Abstract excerpt
Abstract: Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis share common molecular mechanisms involving oxidative stress, neuroinflammation, and microvascular dysfunction. These interrelated processes form a self-perpetuating cycle that accelerates neuronal loss and cognitive decline. Oxidative stress triggers mitochondrial impairment and lipid peroxidation, while chron...
Topics
Open a Topic to create a Post that cites this publication.
- Alzheimer's disease research and treatments
- Apelin-related biomedical research
- Cerebrovascular and genetic disorders
- Mitochondrial Function and Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Neurological disorders and treatments
- S100 Proteins and Annexins
Identifiers and source
- Literature Corpus work
- 6b73f1b4-ac06-55c4-92f6-8c3b130363c4
- DOI
- 10.20944/preprints202511.0551.v1