Article

SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium

2022-01-20

Abstract excerpt

In late 2021, the highly mutated SARS-CoV-2 Omicron variant emerged, raising concerns about its potential extensive immune evasion, increased transmissibility and pathogenicity. Here, we used organoids of the human airways and alveoli to investigate Omicron’s fitness and replicative potential in comparison with earlier SARS-CoV-2 variants. We report that Omicron replicates more rapidly in the airways and has an in...

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Literature Corpus work: 79790cfc-4cce-5804-a61b-296ebd8817ff
DOI: 10.1101/2022.01.19.476898

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