Article

Associations of insomnia on pregnancy and perinatal outcomes: Findings from Mendelian randomization and conventional observational studies in up to 356,069 women

2021-10-10

Abstract excerpt

<h4>Background</h4> Insomnia is common and associated with adverse pregnancy and perinatal outcomes in observational studies. Our aim was to test whether insomnia causes stillbirth, miscarriage, gestational diabetes, hypertensive disorders of pregnancy, perinatal depression, preterm birth, or low/high offspring birthweight (LBW/HBW). <h4>Methods and Findings</h4> We used two-sample Mendelian randomization (MR) wit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6ac7495c-b0f0-5195-84bb-4f2d709f9593
DOI: 10.1101/2021.10.07.21264689

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Associations of insomnia on pregnancy and perinatal outcomes: Findings from Mendelian randomization and conventional observational studies in up to 356,069 womenDOI 10.1101/2021.10.07.21264689Read

Associations between insomnia and pregnancy and perinatal outcomes: Evidence from mendelian randomization and multivariable regression analyses.Semantic proximity Read

Causal associations of Insomnia and postpartum depression: a two-sample mendelian randomization study.Semantic proximity Read

Identifying the potential role of insomnia on multimorbidity: A Mendelian randomization phenome-wide association study in UK BiobankSemantic proximity Read

Exploring and mitigating potential bias when genetic instrumental variables are associated with multiple non-exposure traits in Mendelian randomization.Semantic proximity Read

Identifying the potential causal role of insomnia symptoms on 11,409 health-related outcomes: a phenome-wide Mendelian randomisation analysis in UK Biobank.Semantic proximity Read

Genetic liability to insomnia in relation to cardiovascular diseases: a Mendelian randomisation study.Semantic proximity Read

[Association between insomnia and type 2 diabetes: A two-sample Mendelian rando-mization study].Semantic proximity Read

Causal relationship between insomnia and both socio-economic status and individual behavior: a Mendelian randomization analysisSemantic proximity Read

The Causal Effects of Insomnia on Bipolar Disorder, Depression, and Schizophrenia: A Two-Sample Mendelian Randomization StudySemantic proximity Read

The bidirectional causal relationships of insomnia with five major psychiatric disorders: A Mendelian randomization studySemantic proximity Read

Genetically determined body mass index and maternal outcomes of pregnancy: a two-sample Mendelian randomization studySemantic proximity Read

Genetically Predicted Insomnia in Relation to 14 Cardiovascular Conditions and 17 Cardiometabolic Risk Factors: A Mendelian Randomization Study.Semantic proximity Read