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Article

Associations between insomnia and pregnancy and perinatal outcomes: Evidence from mendelian randomization and multivariable regression analyses.

PLoS medicine - 1 Sept 2022

Yang Qian, Borges Maria Carolina, Sanderson Eleanor, Magnus Maria C, Kilpi Fanny, Collings Paul J, Soares Ana Luiza, West Jane, Magnus Per, Wright John, Håberg Siri E, Tilling Kate, Lawlor Deborah A

Abstract excerpt

BACKGROUND: Insomnia is common and associated with adverse pregnancy and perinatal outcomes in observational studies. However, those associations could be vulnerable to residual confounding or reverse causality. Our aim was to estimate the association of insomnia with stillbirth, miscarriage, gestational diabetes (GD), hypertensive disorders of pregnancy (HDP), perinatal depression, preterm birth (PTB), and...

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Identifiers

PMID: 36067251
DOI: 10.1371/journal.pmed.1004090
PMCID: PMC9488815

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