Article

Fetal loss in pregnant rhesus macaques infected with high-dose African-lineage Zika virus

2022-03-22

Abstract excerpt

Countermeasures against Zika virus (ZIKV), including vaccines, are frequently tested in nonhuman primates (NHP). Macaque models are important for understanding how ZIKV infections impact human pregnancy due to similarities in placental development. The lack of consistent adverse pregnancy outcomes in ZIKV-affected pregnancies poses a challenge in macaque studies where group sizes are often small (4-8 animals). Stu...

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Literature Corpus work: 6aa17dac-48f1-5f84-9761-3a0a380a09a9
DOI: 10.1101/2022.03.21.485088

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