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Animal Models of Zika Virus Infection during Pregnancy

31 Oct 2018

Abstract excerpt

Zika virus (ZIKV) emerged suddenly in the Americas in 2015 and was associated with a widespread outbreak of microcephaly and other severe congenital abnormalities in infants born to mothers infected during pregnancy. Vertical transmission of ZIKV in humans was confirmed when viral RNA was detected in fetal and placental tissues, and this outcome has been recapitulated experimentally in animals. Unlike other...

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PMID: 30384472
DOI: 10.3390/v10110598

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