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Article

Embryotoxic impact of Zika virus in a rhesus macaque in vitro implantation model†

4 Jan 2020

Abstract excerpt

Zika virus (ZIKV) infection is associated with adverse pregnancy outcomes in humans, and infection in the first trimester can lead to miscarriage and stillbirth. Vertical and sexual transmissions of ZIKV have been demonstrated, yet the impact of infection during the initial stages of pregnancy remains unexplored. Here we defined the impact of ZIKV on early embryonic and placental development with a rhesus macaque...

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PMID: 31901091
DOI: 10.1093/biolre/ioz236

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