Article

Efficacy and Safety of GAD- alum Immunotherapy in recent onset Type-1 diabetes: A systematic review and meta-analysis

2026-06-16

Abstract excerpt

<title>Abstract</title> <p>Background GAD-alum (glutamic acid decarboxylase adsorbed to aluminium hydroxide) is an antigen-specific immunotherapy for recent-onset type 1 diabetes mellitus (T1DM). Randomized controlled trials (RCTs) have reported inconclusive results, potentially due to differences in HLA genotype, route of administration, and dosing regimens. This systematic review and meta-analysis evaluated th...

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Literature Corpus work: 6a6abba0-fdb0-5276-86c0-f917a4f4bc91
DOI: 10.21203/rs.3.rs-10043098/v1

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