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Article

Improving clinical utility of GAD65 autoantibodies by electrochemiluminescence assay and clinical phenotype when identifying autoimmune adult-onset diabetes.

Diabetologia - 1 Sept 2021

Gu Yong, Jia Xiaofan, Vartak Tanwi, Miao Dongmei, Dong Fran, Jerram Samuel T, Rewers Marian, Ferrara Assiamira, Lawrence Jean M, Yu Liping, Leslie R David

Abstract excerpt

AIMS/HYPOTHESIS: It is important to differentiate the two major phenotypes of adult-onset diabetes, autoimmune type 1 diabetes and non-autoimmune type 2 diabetes, especially as type 1 diabetes presents in adulthood. Serum GAD65 autoantibodies (GADA) are the most sensitive biomarker for adult-onset autoimmune type 1 diabetes, but the clinical value of GADA by current standard radiobinding assays (RBA) remains...

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Identifiers

PMID: 34272582
DOI: 10.1007/s00125-021-05492-6
PMCID: PMC8382643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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