Article

CENPU Promotes Growth and Metastasis in Nasopharyngeal Carcinoma by Inhibiting DUSP6

2021-12-22

Abstract excerpt

<h4>Background: </h4> Centromere protein U (CENPU), a centromere component, is key for mitosis and involved in the carcinogenesis of cancers. The role and mechanisms of CENPU in nasopharyngeal carcinoma (NPC) has not been described. <h4>Methods: </h4>: CENPU expression in NPC cells and tissues was evaluated by RT-PCR and western blotting. Clinical significance of CENPU was evaluated by Immunohistochemistry. Biolog...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 041813fc-c692-5cb3-bc00-16fbe2cc1e09
DOI: 10.21203/rs.3.rs-1120474/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CENPU Promotes Growth and Metastasis in Nasopharyngeal Carcinoma by Inhibiting DUSP6DOI 10.21203/rs.3.rs-1120474/v1Read

A positive feedback loop of CENPU/E2F6/E2F1 facilitates proliferation and metastasis via ubiquitination of E2F6 in hepatocellular carcinomaSemantic proximity Read

Centromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survivalSemantic proximity Read

The lncRNA GATA3-AS1/miR-495-3p/CENPU axis predicts poor prognosis of breast cancer via the PLK1 signaling pathway.Semantic proximity Read

Prognostic and immune infiltrative biomarkers of CENPO in pan- cancer and its relationship with lung adenocarcinoma cell proliferation and metastasisSemantic proximity Read

CENPE is a potentially key molecular biomarker and potential therapeutic target for lung adenocarcinomaSemantic proximity Read

CENPN Acts as a Novel Biomarker that Correlates With the Malignant Phenotypes of Glioma CellsSemantic proximity Read

CENPA facilitates hepatocellular carcinoma proliferation by cooperating with YY1 to drive transcription of CCND1 and NRP2.Semantic proximity Read

Pan-cancer landscape of CENPO and its underlying mechanism in LUADSemantic proximity Read

Identification of an oncogenic role of centromere protein M in non-small cell lung cancer via CDC20/MYBL2/Wnt signalsSemantic proximity Read

High CENPM Gene Expression Predict Poor Survival Outcome in Lung AdenocarcinomaSemantic proximity Read

Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinomaSemantic proximity Read

Decreased Expression of NUSAP1 Predicts Poor Overall Survival in Cervical CancerSemantic proximity Read