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A Synthetic ERRα Agonist Induces an Acute Aerobic Exercise Response and Enhances Exercise Capacity

2022-10-07

Abstract excerpt

<h4>ABSTRACT</h4> Repetitive physical exercise induces physiological adaptations in skeletal muscle that improves exercise performance and is effective for the prevention and treatment of several diseases. Here we report the identification of a synthetic agonist for the orphan nuclear receptor ERRα (estrogen receptor-related receptor α), SLU-PP-332, that activates an acute aerobic exercise genetic program in skel...

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Literature Corpus work
6a5b0dc6-05d2-519a-b9f3-6a28696aee5d
DOI
10.1101/2022.10.05.510974
Open publication

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