Article

TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment

2020-08-15

Abstract excerpt

Cancer immunotherapy targeting co-inhibitory pathways by checkpoint blockade shows remarkable efficacy in a variety of cancer types. However, only a minority of patients respond to treatment due to the stochastic heterogeneity of tumor microenvironment (TME). Recent advances in single-cell RNA-seq technologies enabled comprehensive characterization of the immune system heterogeneity in tumors, but also posed compu...

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Literature Corpus work: 69d9d05c-59ed-5a52-a2b1-2a6e78a2414a
DOI: 10.1101/2020.08.15.251959

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