Article

Apomorphine is a potent inhibitor of ferroptosis independent of dopaminergic receptors

2023-10-03

Abstract excerpt

Originally, apomorphine was a broad-spectrum dopamine agonist with an affinity for all subtypes of the Dopamine D1 receptor to the D5 receptor. We previously identified apomorphine as a potential therapeutic agent for mitochondrial diseases by screening a chemical library of fibroblasts from patients with mitochondrial diseases. In this study, we showed that apomorphine prevented ferroptosis in fibroblasts from va...

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Literature Corpus work: 69b4a823-3446-59ad-b9bb-b93085fbf7da
DOI: 10.21203/rs.3.rs-3361719/v1

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