Article

Human papillomavirus type 16 circular RNA is barely detectable for the claimed transformation activity

2021-09-23

Abstract excerpt

The human papillomavirus type 16 (HPV16) E7 oncoprotein plays an essential role in cervical carcinogenesis and is encoded predominantly by a viral E6*I mRNA through alternative RNA splicing of a p97 promoter-transcribed bicistronic E6E7 pre-mRNA. Recently, Zhao et al. detected the HPV16 circular RNA circE7, which is generated aberrantly through backsplicing of the E6E7 pre-mRNA from two HPV16-positive cervical can...

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Literature Corpus work: 6972b89d-e5f9-5b4c-bae3-dccb8369841c
DOI: 10.1101/2021.09.22.449294

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