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Article

Downregulation of lncRNA CCAT1 enhances 5-fluorouracil sensitivity in human colon cancer cells

23 Apr 2019

Abstract excerpt

The purpose of this study was to determine the aberrant expression of the long noncoding RNA (lncRNA) colon cancer-associated transcript 1 (CCAT1) in 5-fluorouracil-resistant colonic neoplasm cells and to elucidate its effects on the 5-fluorouracil sensitivity of human colonic neoplasm cells. The aberrant expression of lncRNAs in normal tissues and colonic neoplasm tissues was detected by microarray assay....

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PMID: 31039730
DOI: 10.1186/s12860-019-0188-1

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