Article

scPanel: A tool for automatic identification of sparse gene panels for generalizable patient classification using scRNA-seq datasets

2024-04-11

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) technologies can generate transcriptomic profiles at a single-cell resolution in large patient cohorts, facilitating discovery of gene and cellular biomarkers for disease. Yet, when the number of biomarker genes is large the translation to clinical applications is challenging due to prohibitive sequencing costs. Here we introduce scPanel, a computational framework designed to...

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Literature Corpus work: 694c8f22-2953-5741-b287-398e7fa89552
DOI: 10.1101/2024.04.09.588647

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