Article

scGPD: single-cell informed gene panel design for targeted spatial transcriptomics

2025-10-03

Abstract excerpt

In targeted spatial transcriptomics technologies, a key challenge is to select an informative gene panel that captures the complexity of cellular and spatial heterogeneity within tissues. Many existing methods use prior knowledge or heuristic selection rules, such as selecting highly variable genes, which overlook gene-gene correlations and may consequently result in suboptimal coverage. To address the limitations...

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Literature Corpus work: b48bbbc5-518d-5e23-8d47-3551d32f664b
DOI: 10.1101/2025.10.02.680117

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