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Three Plasmid Strategies, One Intermediate Convergence State: Lineage-Specific Resistance–Virulence Architecture in Dominant Indian Carbapenem-Resistant <i>Klebsiella pneumoniae</i> Clones

2026-06-24

Abstract excerpt

Carbapenem-resistant Klebsiella pneumoniae (CRKp) is a critical global healthcare threat driven by high-risk multidrug-resistant (MDR) clones that acquire hypervirulence genes. Although resistance-virulence co-occurrence is extensively documented, the plasmid-level mechanisms facilitating this convergence remain unclear. In this study, we utilized hybrid short- and long-read whole-genome sequencing of 376 clinica...

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Literature Corpus work
690c5190-c042-5961-967b-8a728fe20df4
DOI
10.64898/2026.06.23.734134
Open publication

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Three Plasmid Strategies, One Intermediate Convergence State: Lineage-Specific Resistance–Virulence Architecture in Dominant Indian Carbapenem-Resistant <i>Klebsiella pneumoniae</i> ClonesDOI 10.64898/2026.06.23.734134
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