Article

Genetic correlation and causality of cancers and Parkinson’s disease

2020-10-12

Abstract excerpt

<h4>Background and objectives</h4> Most cancers appear with reduced frequency in Parkinson’s disease (PD), but the prevalence of melanoma and brain cancers are often reported to be increased. Shared genetic architecture and causal relationships to explain these associations have not been fully explored. <h4>Methods</h4> Linkage disequilibrium score regression (LDSC) was applied for five cancer studies with availab...

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Literature Corpus work: 68ce62ab-0445-5079-a8c3-3d6f857cf127
DOI: 10.1101/2020.10.07.20208124

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