Article

Functional and Early Folding Residues are separated in proteins to increase evolvability and robustness

2018-03-28

Abstract excerpt

The three-dimensional structure of proteins captures evolutionary ancestry, and serves as starting point to understand the origin of diseases. Proteins adopt their structure autonomously by the process of protein folding. Over the last decades, the folding process of several proteins has been studied with temporal and spatial resolution which allowed the identification of so-called Early Folding Residues (EFR) in...

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Literature Corpus work: 68cb1bb3-6b62-563d-adf1-88893053ed8f
DOI: 10.1101/290627

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