Article

Heterogeneous folding landscapes and predetermined breaking points within a protein family

2024-04-26

Abstract excerpt

The accurate prediction of protein structures with artificial intelligence has been a spectacular success. Yet, how proteins fold into their native structures inside the cell remains incompletely understood. Of particular interest is to rationalize how proteins interact with the protein homeostasis network, an organism specific set of protein folding and quality control enzymes. Failure of protein homeostasis lead...

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Literature Corpus work: 37b32d54-cce9-50af-8091-6291d763d72e
DOI: 10.1101/2024.04.22.590563

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